Product name:

Dihydroergocristine Mesylate

Empirical formula:

C₃₅H₄₁N₅O₅ . CH₄ O₃S

Molecular weight:

707.8

CAS:

[24730-10-7]

Description:

White crystalline powder

Identity

    IR spectrum:

Complies

    TLC:

Complies

    Methansulfonic acid:

Complies

Appearance of the solution:

Complies

Value of pH:

4.0 - 5.0

Specific optical rotation in dried substance:

-43 to -37°

Related substances:

    Dihydro-alfa-ergocryptine:

NMT 0.5%

    Dihydroergosedmine:

NMT 0.3%

    Dihydroergocristine-N6-oxide:

NMT 0.3%

    Other individual (HPLC):

NMT 0.1%

    Total impurities:

NMT 2.0%

Loss on drying:

NMT 3.0%

Assay

    In dried substance (tirt.):

98.0 – 102.0%

Residual solvents

    Ethanol:

    1,4-dioxan:

NMT 380 ppm

    Ethyl acetate:

NMT 5,000 ppm

    Methanol:

NMT 3,000 ppm

    Dichloromethane:

NMT 600 ppm